CRISPR-CAS9 [Team 1150]

By mackennaw24 | Updated: Nov. 24, 2024, 7:52 p.m.

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Tufts University Mini-Med In Person 2022 Phuong To, Mackenna Ward, Ai Mei Zhang As Tufts Mini-Med students, we collaboratively researched about CRISPR-Cas9, a genome editing technique developed by Emmanuelle Charpentier and Jennifer Doudna. There has been initial trials on this technique, yet many people hold different opinions on the future usage of CRISPR-Cas9 and its lasting effects. Sources: https://docs.google.com/document/d/1G_dnqMR2_mORbLlsTATnP_6aTh0DxDl8tXF1qzKhwuU/edit

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CRISPR Cas9
By Phuong To, Ai Mei Zhang, and Mackenna Ward
Tufts Mini Med Capstone Project
What is 
CRISPR Cas9?
Gene Modification
Changes in the sequences of DNA to:
- Enhance certain traits
- Prevent genetic disease
Gene Modification
Green Revolution:
-  In the 1950s and 60s
-  Genetically modified Seeds
-  Creates agricultural crops that are bigger and produce more food

Cystic Fibrosis

Hemophilia

Sickle Cell Disease

CRISPR CAS9 TECHNIQUE
C
R
 I
S
P
R
lustured
egularly
nterspaced
hort
alendromic
epeats
What does CRISPR Cas9 even stand for?
E. Coli: bacteria that uses CRISPR as its adaptive immune system for protecting its bacterial cells from foreign agents like bacteriophage and their genomes.
How does CRISPR Cas9 work?
WHAT IF WE CAN USE
 THIS SYSTEM ON
HUMANS?
Emmanuelle Charpentier and Jennifer A. Doudna
(Creators of the CRISPR Cas9 Technique)
Ethical Concerns
Benefits of CRISPR Cas9: 
Concerns about CRISPR Cas9: 
Mistakes could disastrous consequences
Has the potential to propagate eugenics
Only accessible to the super-wealthy

Decrease in biodiversity

Patenting of CRISPR techniques would make it less accessible
Clinical trials to cure genetic diseases show promising results

Trials in mice prove effective in prohibiting the progression of cancer and tumor growth
What will happen with the CRISPR Cas9 technique in the future?
Who gets to decide when we use CRISPR?
THANK YOU!
How and when should it be used?

CRISPR-CAS9 [Team 1150]

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